The Longitudinal Idiopathic Intracranial Hypertension Trial: Outcomes From Months 6–12
نویسندگان
چکیده
منابع مشابه
The Longitudinal Idiopathic Intracranial Hypertension Trial: Outcomes From Months 6-12.
PURPOSE To determine whether the beneficial effects of acetazolamide (ACZ) in improving vision at 6 months continues to month 12 in participants of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT). DESIGN Nonrandomized clinical study. METHODS In the IIHTT, subjects were randomly assigned to placebo-plus-diet or maximally tolerated dosage of acetazolamide-plus-diet. At 6 mont...
متن کاملPapilledema Outcomes from the Optical Coherence Tomography Substudy of the Idiopathic Intracranial Hypertension Treatment Trial.
PURPOSE To assess treatment efficacy using spectral-domain (SD) optical coherence tomography (OCT) measurements of papilledema in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT), which evaluated the effects of acetazolamide and weight management and of placebo and weight management in eyes with mild visual loss. DESIGN Randomized double-masked control clinical trial of acetaz...
متن کاملVisual Field Outcomes for the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT)
PURPOSE The Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) showed that acetazolamide provided a modest, significant improvement in mean deviation (MD). Here, we further analyze visual field changes over the 6-month study period. METHODS Of 165 subjects with mild visual loss in the IIHTT, 125 had perimetry at baseline and 6 months. We evaluated pointwise linear regression of visu...
متن کاملThe idiopathic intracranial hypertension treatment trial: design considerations and methods.
BACKGROUND The objectives of this study were to present the rationale for the main aspects of the study design and describe the trial methodology for the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT). METHODS Eligible candidates with mild visual field loss (automated perimetric mean deviation [PMD] -2 to -7 dB) were randomized to receive either acetazolamide or matching placebo...
متن کاملFactors Affecting Visual Field Outcomes in the Idiopathic Intracranial Hypertension Treatment Trial.
BACKGROUND To determine the prevalence of visual field (VF) performance failures (PF) and treatment failures (TFs), and identify factors associated with PFs in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT). METHODS A total of 165 participants from 38 sites with idiopathic intracranial hypertension (IIH) and mild visual loss were randomized to either acetazolamide-plus diet ...
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ژورنال
عنوان ژورنال: American Journal of Ophthalmology
سال: 2017
ISSN: 0002-9394
DOI: 10.1016/j.ajo.2017.01.004